Allogenic Cultured Limbal Epithelial Transplantation and Cultivated Oral Mucosal Epithelial Transplantation in Limbal Stem Cells Deficiency: A Comparative Study, Ophthalmology and Therapy, 14, 2 ...

Limbal stem-cell deficiency is a rare disease affecting the eye that can lead to blindness. It occurs when stem cells in the cornea cannot regenerate and repair the surface, leading to the ...

Source Reference: Jurkunas UV, et al "Cultivated autologous limbal epithelial cell (CALEC) transplantation for limbal stem cell deficiency: A phase I/II clinical trial of the first xenobiotic-free ...

“The limbal stem cells are cells that we are born with and then do not produce any additional during our lifetime, so if there’s damage to those, it’s somewhat irreversible,” Bert explained.

In this new process, stem cells taken from a person's healthy eye can be used to rebuild the cornea in their damaged eye, researchers reported March 4 in the journal Nature Communications.. The ...

“The limbal stem cells are cells that we are born with and then do not produce any additional during our lifetime, so if there’s damage to those, it’s somewhat irreversible,” Bert explained.

When a person’s cornea is damaged, the injury can deplete the limbal epithelial cells. As a result, the surface of the eye develops permanent damage -- a condition called limbal stem cell ...

This depletion is called a limbal stem cell deficiency and it leaves people with a permanently damaged corneal surface, meaning that a typical corneal graft can’t be a lasting treatment (without ...

It contains important limbal epithelial stem cells, which help repair minor injuries. However, in cases of thermal or chemical burns, ...

The resulting limbal stem cell deficiency renders the eye with a permanently damaged surface where it can't undergo a corneal transplant, the current standard of care for vision rehabilitation.

WEDNESDAY, March 5, 2025 (HealthDay News) -- Sight-robbing injuries to the cornea can be repaired using a groundbreaking experimental stem cell treatment, a new study shows. The cornea -- the ...