Our group is focused on understanding the role of endothelial and stem cells in heart and skeletal muscle diseases, metabolic regulation as well as in cancer. The major interest is in the endothelial ...

As expected, the liver stem cells required Wnt signals to maintain their stem cell identity. Nusse’s team discovered that endothelial cells lining the central vein, the blood vessel around which the ...

For example, the endothelial tissue that lines the human ... typically every few days. Whenever stem cells are called upon to generate a particular type of cell, they undergo an asymmetric cell ...

The researchers utilized commercially available endothelial cell lines as feeder cells, adding only two signaling molecules: stem cell factor (SCF) and thrombopoietin (TPO). The result was the ...

The researchers utilized commercially available endothelial cell lines as feeder cells, adding only two signaling molecules: stem cell factor (SCF) and thrombopoietin (TPO). The result was the ...

Discover how preleukemic stem cells alter the bone marrow microenvironment, promoting leukemia growth. This study reveals key ...

These newly discovered cells, named EndoMac progenitors, have the remarkable capability to differentiate into two distinct ...

Treatment options for wet macular degeneration include anti-vascular endothelial growth factor ... research into innovative therapies such as stem cell therapy, gene therapy, and implantable ...

Two projects from the Josep Carreras Leukaemia Research Institute have received funding from the highly competitive ERC ...

An RNA-editing gene therapy has been developed that switches off the key driver of common eye conditions affecting diabetics ...

University of Helsinki, 2017- Research Interests: Genetics of congenital heart disease, Left ventricular outflow tract obstruction (LVOTO) defects, Patient-derived iPS cells in disease modeling, ...