More information: Mingliang Jin et al, Dynamic allostery drives autocrine and paracrine TGF-β signaling, Cell (2024). DOI: 10 ...

Indeed, TGF-β family proteins can, through paracrine or autocrine signalling mechanisms, induce cells that have acquired cell differentiation characteristics of one particular lineage to switch ...

Cell production of substances such as catecholamines, acetylcholine and glutamate acting on their receptors, which allow autocrine/paracrine signalling, has been described,39 which may explain pain in ...

This one day workshop provides an insight into the workings of common railway signalling subsystems such as train detection, signal mechanisms, switch mechanisms, interlocking and operator interface.

Thus, cutaneous IL-36 signaling is crucial for the immunopathological ... and TNF-α that are released in an autocrine fashion and form an inflammatory loop." In my original commentary on IL ...

The most potent stimulus to collagen I production is TGF-beta, which is derived from both paracrine and autocrine sources. Lipid peroxidation products are emerging as important stimuli to ECM ...

Members of the Proud Boys, key instigators in the Jan. 6, 2021, Capitol riot, are mobilizing in support of Donald Trump—and in some cases, making threats about the presidential election. While ...

Ding, B. , Wu, Y. , Zhang, Y. and Li, Y. (2024) CXCL10 Induces Lytic Reactivation of EBV through EXTL 1. Advances in ...

Human cell transformation systems revealed that RAL-GEF signaling is particularly required for oncogenic RAS function in human cancer. Murine Kras-driven lung cancer models have confirmed the key ...

The box was retired in 2019 after the Norwich to Yarmouth and Lowestoft railway lines were upgraded to a digital system Volunteers who have brought a railway signalling box back to life hope to ...