Here’s the full Chiefs 2025 schedule: Friday, Aug. 22: Chicago, 7:20 p.m., Channel 41 Friday, Sept. 5: at L.A. Chargers (in Sao Paulo, Brazil), 7 p.m., YouTube Sunday, Sept. 14: Philadelphia, 3:25 p.m., FOX Sunday, Sept. 21: at New York Giants, 7:20 p.m., NBC Sunday, Sept. 28: Baltimore, 3:25 p.m., CBS

D with matchup details. NFL Commissioner Roger Goodell said that the Kansas City Chiefs will face the L.A. Chargers in an early-September game streaming globally on YouTube. The commissioner made the announcement Wednesday night at YouTube’s Brandcast event for advertisers.

Kansas City Chiefs will officially open the 2025 season against the Los Angeles Chargers in São Paulo, Brazil | @EdEastonJr

Many Brazilian fans are overjoyed by the news that the Chiefs will play in Brazil on Sept. 5, facing the Chargers. For many, it’s the chance to watch their favorite team in person for the first time.

While the matchup has not yet been officially announced, the Kansas City Chiefs will reportedly be the nominal "road" team facing the Los Angeles Chargers in São Paulo, Brazil in Week 1 of the 2025 NFL season.

The 2025 schedule just dropped, and we are analyzing every game the Chiefs will play this season, and how they will do in each contest.

The Chiefs, who open the 2025 season on a different continent for the first time ever, playing the Los Angeles Chargers in the NFL's Sao Paulo game in Brazil, leave the bells and whistles to others and go pretty no-nonsense here in the schedule video.

The announcement of Kansas City’s Week 1 trip to Brazil could be a bit of a homecoming for one member of Chiefs Kingdom.